Document Type : Original Article

Authors

1 MSc Student of Sports physiology, sports physiology and nutrition, Department of Exercise Physiology, Sport Sciences Research Institute of Iran, Tehran, Iran

2 Department of Exercise Physiology and Sport Injuries and Corrective Movements, Faculty of Sport Sciences, Ferdowsi University of Mashhad, Mashhad, Iran, Sports Science Research Assistant, Skill National University, Tehran, Iran

10.22054/jshsr.2025.84830.1018

Abstract

Vitamin B12 (cobalamin), as a water-soluble vitamin, plays a vital role in energy metabolism, red blood cell production, and nerve function. Athletes have a higher need for this vitamin due to intense physical activities, and in medical science, one of the uses of this vitamin is to help improve respiratory status and oxygenation in the body. Taking vitamin B12 supplements has been considered a strategy to improve sports performance. This review article examines the effect of vitamin B12 supplementation on aerobic performance in athletes.

Using a systematic approach, this study collected articles on the effect of vitamin B12 on aerobic performance in athletes from reputable databases such as PubMed, Scopus, and Google Scholar. The inclusion criteria included experimental and clinical studies published in the last ten years focusing on the effect of vitamin B12 supplementation on aerobic performance. After identifying the articles, information related to study design, number of participants, dose and duration of supplementation, and main results were extracted and analyzed.

The results of the study showed that vitamin B12 supplementation can significantly improve the aerobic performance of athletes. Studies have shown that this vitamin is associated with increased oxygen consumption capacity (VO2 max), reduced muscle fatigue, and improved recovery time after exercise. There is also evidence that vitamin B12 has a positive effect on energy metabolism and increased performance in long-term exercise. Based on the results of this review, vitamin B12 supplementation can be considered an effective strategy for improving aerobic performance in athletes. However, more research is needed to determine the appropriate dosage, duration of use, and possible side effects. Athletes should also consult with a nutritionist before starting supplements to get the best results from their training programs.

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